Specializing in RSMs, Intermediates, and Ingredients

Our highly-qualified technical team solves complex challenges in custom chemical synthesis and scale-up from pre-clinical through commercialization. We offer customized product development, project management, and a deep understanding of organic synthesis supported by a cGMP environment.

The facility provides the vital building blocks for a range of products with high quality, high purity, made-to-order compounds that can be manufactured in quantities ranging from kilos to tons, delivered on time, and upholding the highest safety and quality standards.

Albany’s core products and capabilities include:

  • Chiral building blocks
  • Custom boronic acids
  • Solution phase peptides
  • Specialty amino acids
  • Dietary ingredients
  • Air sensitive chemistry
  • cGMP pharma manufacturing
  • Analytical method development and validation
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    R&D Capabilities

    • Six staff chemists (3 Ph.D, 2 MS, 1 BS)
    • Large lab with 12 dedicated fume hoods
    • Microscale up to 50L vessel reaction capability
    • Nutsche filters
    • Fractional distillation (1-760 Torr, 25-250°C)
    • Hydrogenation (100 mL to 2 L, 0-75 PSI)
    • Dedicated R&D HPLCs and GCs
    • Onsite NMR
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    Pilot Scale Capabilities

    • Two separate pilot facilities on-site
    • Reactors range from 30 to 500 gallons (115 – 1,900 L)
    • Glass-lined, stainless steel, and Hastelloy® alloy

    Filters & Dryers

    • 32” Centrifuge SS
    • 0.67 M2 Comber HASTELLOY® Filter Dryer
    • 0.1 M2 AURORA® HASTELLOY® Filter Dryer (2x)
    • 0.67 M2 Cogeim HASTELLOY® Filter Dryer
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    Analytical Capabilities

    • HPLC / HPLC-MS / HPLC-CAD / HPLC-ELSD
    • UPLC
    • GC / GC-MS / GC-HS
    • FTIR / NMR
    • LOD, KF
    • ICP-OES
    • Malvern
    • Standard wet chemistry (USP and internal methods)
    • Polarimeter
    • Separate cGMP release laboratory
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    cGMP Kilo Suite

    • Clean room design with airlock and custom 12’ walk-in hood
    • Chemglass all glass vessels
      • 15 L, 30 L, 50 L, 75 L, 100 L
    • Huber 915 temperature controller
    • Operational ranges
      • -60°C to 200°C
      • 2 Torr to 10 psi
    • Isolation & Drying
      • 0.2 M2 AURORA® 316L SS Filter Dryer
      • Nutsche filters
      • Vacuum ovens
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    Commercial Manufacturing

    Reactors

    • Over 18,500 gallons (70,000L) of capacity
    • Sizes range from 500 to 2,000 gallons (1,900 – 7,600 L)
    • Glass-lined, stainless steel, and Hastelloy® alloy
    • Temperatures –20ºC to 110ºC
    • Hydrogenation (up to 75 psig / ~5 bar)

    Filters & Dryers

    • 48” Stainless Steel Centrifuges (3)
    • 1.0 M2 HASTELLOY® Filter Dryer
    • 2.2 M3 Stainless steel Rotary Dryer
    • 1.1 M3 Stainless steel Tray Dryers (2x)

GRACE® is a trademark, registered in the United States and/or other countries, of W. R. Grace & Co.-Conn. HASTELLOY® is a trademark, registered in the United States and/or other countries, of Haynes International, Inc. AURORA® is a trademark, registered in the United States and/or other countries, of All-Weld Company Limited. This brochure is an independent publication and is not affiliated with, nor has it been authorized, sponsored, or otherwise approved by the aforesaid company. This trademark list has been compiled using available published information as of the publication date of this brochure and may not accurately reflect current trademark ownership or status. © Copyright 2021 W. R. Grace & Co.-Conn. All rights reserved.

 

Facilities

Tyrone, PA

Our Tyrone, Pennsylvania facility has more than 40 years of history in custom manufacturing and is where we develop or reverse integrate RSMs under non-GMP conditions.

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Facilities

South Haven, MI

Our South Haven, Michigan facility is a full-service cGMP manufacturing site, containing everything required to develop APIs to commercialization, with all the necessary support capabilities.

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